News




Home News Technical articles Application of sterilizing filtration products in injection production process

Application of sterilizing filtration products in injection production process

2024-03-12 Eternalwater

Injections refer to raw materials or sterile preparations made with appropriate excipients for injection into the body. Injections are divided into large-volume injections (large infusion or LVP), small-volume injections (small injections or SVP) and powder injections according to their production technology characteristics and production processes. Among them: large-volume injection (LVP) is commonly known as large infusion, which refers to a volume of ≥ 50ml liquid sterilization preparation that is directly injected into the vein; small volume injection (SVP), commonly known as water injection, configures the drug into a solution (aqueous or non-aqueous), suspension or emulsion, and puts it into an ampoule or multi-dose container. The prepared sterile preparation has a general capacity of ≤20mL.




membrane pleated filter cartridge


Due to the particularity of the administration site of this type of preparation, its quality requirements and safety risks are very high. The sterility of the final product must be ensured, that is, the drug cannot contain bacteria and other microorganisms. This is also an important guarantee to ensure patient safety. Therefore, sterile filtration is particularly important in the entire process.

Filtration is widely used in different process stages of large and small volume injections. It mainly includes decarbonization filtration, particle removal and pre-filtration to reduce microbial load, gas sterilization filtration, redundant filtration and sterilization filtration of end products. etc. The main filtering sites are:
pleated filter cartridge factory
1. Decarbonization filtration: remove activated carbon particles and colloidal impurities, extending the service life of downstream filters
2. Pre-filtration (particle removal): further remove activated carbon particles and colloidal impurities, extending the service life of downstream filters
3. Pre-filtration (reduce microbial load): Reduce microbial load and extend the service life of downstream sterilization filter elements
4. Redundant filtration: remove bacteria and microorganisms in the filtrate
5. Terminal sterilization filtration: remove bacteria and microorganisms in the terminal filtrate
6. Respirator: balance tank pressure and prevent pollution

Common large and small volume injection production processes



Latest News



The 67th (2025 Autumn) China National Pharmaceutical Machinery Exposition
The 67th (2025 Autumn) China National Pharmaceutical Machinery Exposition
Committed to Promoting the Sustainable Development of China's Pharmaceutical Equipment Industry The National Pharmaceutical Machinery Expo and China International Pharmaceutical Machinery Expo
Read more 2025-10-13
About WESEMIBAY(2025 WESEMiBAY Semiconductor Conference)
About WESEMIBAY(2025 WESEMiBAY Semiconductor Conference)
The WESEMIBAY Exhibition aims to implement the "One Cluster, One Exhibition" decision-making and deployment of Shenzhen's "20+8" industry. It is guided by China International Engineering Consulting Co
Read more 2025-10-11
National Day Holiday Mid - Autumm Festival Notice
National Day Holiday Mid - Autumm Festival Notice
Please be advised that our office and factory will be closed for the National Day and Mid-Autumn Festival holidays from October 1st to October 8th, 2025 (8 days in total). Normal operations will resum
Read more 2025-09-28
CPHI&PMEC 2025 Perfect ending
CPHI&PMEC 2025 Perfect ending
The three-day exhibition joined hands with more than 3,500 domestic and foreign exhibitors to create a professional exhibition covering the entire pharmaceutical industry chain. The exhibition site wa
Read more 2025-06-27
Eternalwater Filtration invites you to participate in CPHI&PMEC China 2025, see you in Shanghai
Eternalwater Filtration invites you to participate in CPHI&PMEC China 2025, see you in Shanghai
Eternalwater Filtration invites you to participate in CPHI&PMEC China 2025, see you in Shanghai
Read more 2025-06-18
Eternalwater Filtration invites you to participate in BIOCHINA 2025
Eternalwater Filtration invites you to participate in BIOCHINA 2025
BIOCHINA2025 will promote project cooperation between domestic and foreign scientific research, industry, investment, clinical, government and other institutions through diversified forms such as
Read more 2025-02-22
Read more
  • Subscribe for Join Us!



  • Join us and get detail information,technical parameter and new products etc.
CopyRight © Hangzhou Eternalwater Filtration Equipment Co., Ltd. 2002-2025
steel chastity cage best chastity cage men chastity cage stainless steel chastity cage silicone chastity cage chastity cage device best silicone chastity cage masturbation cup huge dildo water filter cartridge