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biological products
- 1. Medium filtration
Culture medium is an artificial nutrient for the growth and maintenance of microorganisms, plants and animal tissues. It is widely used in pharmaceutical processes such as biological fermentation and cell culture.
Because some media will destroy the effective components after high-pressure sterilization, it is necessary to eliminate bacteria and Mycoplasma through filtration to ensure sterility.
Different media contain different components. For media containing more proteins and sugars, multi-stage progressive filtration should be adopted to ensure the filtration capacity and the use efficiency of terminal sterilization filter element.
2. Buffer filtration
A buffer is a solution that resists pH changes when a small amount of acid or base is added. In biopharmaceutical, for example, buffer is used in the purification process of vaccines, blood products, monoclonal antibodies and so on. It is recommended to use a sterilizing filter to filter the buffer. If a pre filter is used, it can effectively protect the use of the terminal sterilizing filter. The reason why the buffer is filtered is that, on the one hand, it can protect the service life of the downstream chromatographic column and ultrafiltration membrane, on the other hand, it is to ensure the quality of the final vaccine.
3. Growth factor filtration
Growth factors are cytokines with the activity of stimulating cell growth. They are polypeptide substances that regulate cell growth and other functions by inducing binding with specific cell membrane receptors. At present, most growth factors are obtained through bioengineering technology, such as insulin.
4. Monoclonal antibody (mAb) is an antibody prepared by monoclonal technology. At present, large pharmaceutical enterprises have joined the field of mAb. In the process of McAb harvesting and purification, the target protein should be separated from impurities by purification process.
5. Culture medium
Culture medium is an artificial nutrient for the growth and maintenance of microorganisms, plants and animal tissues. It is widely used in pharmaceutical processes such as biological fermentation and cell culture.
Because some media will destroy the effective components after high-pressure sterilization, it is necessary to eliminate bacteria and Mycoplasma through filtration to ensure sterility.
Different media contain different components. For media containing more proteins and sugars, multi-stage progressive filtration should be adopted to ensure the filtration capacity and the use efficiency of terminal sterilization filter element.
related products
- ecs-m series of gamma-resistant hydrophilic capsule filter
- Eternalwater ® Ecs-m series capsule filter is suitable for buffer, culture medium, and HP regulator filter during biological product production.It is equipped with bacteriial hydrophilic polyether sulfoide (PES) filtration membrane, reliable sterilization guarantee, good chemical compatibility, and suitable for various types of liquid filtration in PH range 1-14.
High-throughput sterilizing hydrophilic polyether sulfoone (pes) filtration membrane with rapid filtration with sterilization guarantee, Which can reduce the cost of pre-filtration and the entire filtration process. Good chemical compatibility, suitable for various solutions with ph 1-14, including naoh solution.The e c s-b series of gamma-resistant hydrophilic capsule filter can select for gamma-ray-resistant sterilization, autoclave steam sterilization, and pre-sterilization.
- ecs-b series of gamma-resistant hydrophilic capsule filter
- Eternalwater ® Ecs-b series capsule filter is suitable for buffer, culture medium, and HP regulator filter during biological product production.It is equipped with bacteriial hydrophilic polyether sulfoide (PES) filtration membrane, reliable sterilization guarantee, good chemical compatibility, and suitable for various types of liquid filtration in PH range 1-14.
High-throughput sterilizing hydrophilic polyether sulfoone (pes) filtration membrane with rapid filtration with sterilization guarantee, Which can reduce the cost of pre-filtration and the entire filtration process. Good chemical compatibility, suitable for various solutions with ph 1-14, including naoh solution.The e c s-b series of gamma-resistant hydrophilic capsule filter can select for gamma-ray-resistant sterilization, autoclave steam sterilization, and pre-sterilization.
- PVDF EFV Series
- Hydrophobic polyvinylidene fluoride filter element adopts hydrophobic PVDF membrane, which has high flux and low protein adsorption. The wide chemical compatibility of hydrophobic PVDF membrane makes the filter element suitable for filtration of various acid and alkali solutions.
- PVDF ELV Series
- Hydrophilic PVDF membrane is used for hydrophilic polyvinylidene fluoride filter element,It has high throughput, low protein adsorption, hydrophilic PVDF membrane, wide chemical compatibility, no need of pre wetting. The integrity test before delivery ensures the high quality of products.
- PTFE EKT Series
- It is suitable for gas sterilization and adopts imported hydrophobic PTFE membrane, which has high flux and high sterilization efficiency. The filter element has good heat resistance and can operate steam sterilization for over 150 times.The integrity test before delivery ensures the high quality of products.
- PTFE EFT Series
- The hydrophobic PTFE filter element adopts natural hydrophobic PTFE membrane. The wide chemical compatibility of PTFE membrane makes the filter element suitable for sterilization and filtration of strong solvents, strong corrosive liquids, and strong oxidizing liquids.
- PP EHP Series
- The relative precision polypropylene filter element adopts high efficiency PP membrane, and the characteristics of high flow rate and high contaminant capacity make it the most economical pre filtration filter element. Wide range of uses, factory integrity test to ensure high quality products.
- PP EDP Series
- The multi-layer polypropylene filter element adopts the multi-layer gradient PP membrane structure, whose high pollutant capacity makes it the most economical and efficient filter element.Integrity test before delivery to ensure high quality of products.
- GF -EBGG Series
- The high-efficiency pre-filtering glass fiber pleated filter element is made of ultra-fine glass fiber material. The retention rate is as high as 96%, which effectively protects the terminal sterilization filter element, and is suitable for gas pretreatment and precision filtration
- GF -EBG Series
- The pleated filter element adopts rigid ultra-fine glass fiber (GF) membrane, resulting from its high flow rate and large pollution capacity, adsorption effect, good retention effect, and low leaching characteristics, it becomes an efficient pre-filtration filter element. The integrity test before leaving factory ensures the high quality of the products.
- Cartridge filter Housing
- Stainless steel precision filter is made of SUS316L or SUS304 all stainless steel. With multiple filter elements as filtration units, it has the advantages of high filtration accuracy, fast filtration speed, no leakage, acid and alkali resistance, corrosion resistance, and convenient cleaning. In order to prevent the suspended particles that are not completely removed or newly generated in the pretreatment from entering the reverse osmosis system, and to protect the high-pressure pump and the reverse osmosis membrane, a filter-type security filter is usually installed before the reverse osmosis water enters. It is an ideal filtration equipment for biomedicine, beer and beverage, chemical, water treatment and other industries.
- Bag Filter
- Stainless steel precision filter is made of SUS316L or SUS304 all stainless steel. With multiple filter elements as filtration units, it has the advantages of high filtration accuracy, fast filtration speed, no leakage, acid and alkali resistance, corrosion resistance, and convenient cleaning. In order to prevent the suspended particles that are not completely removed or newly generated in the pretreatment from entering the reverse osmosis system, and to protect the high-pressure pump and the reverse osmosis membrane, a filter-type security filter is usually installed before the reverse osmosis water enters. It is an ideal filtration equipment for biomedicine, beer and beverage, chemical, water treatment and other industries.
- SWG capsule filter
- The capsule filter of SWG series has a variety of volumes for choices. Its cannulated connection for inlet and outlet has the advantages of quick installation and convenient use. The internal filter element can be configured with appropriate membrane material according to the characteristics of the filter material, which has a very wide range of applicability, and it is especially suitable for the filtration of small doses of material liquid.
- NPT capsule filter
- The capsule filter of NPT series has a variety of volumes for choices. Its cannulated connection for inlet and outlet has the advantages of quick installation and convenient use. The internal filter element can be configured with appropriate membrane material according to the characteristics of the filter material, which has a very wide range of applicability, and it is especially suitable for the filtration of small doses of material liquid.
- KZ capsule filter
- The capsule filter of KZ series has a variety of volumes for choices. Its cannulated connection for inlet and outlet has the advantages of quick installation and convenient use. The internal filter element can be configured with appropriate membrane material according to the characteristics of the filter material, which has a very wide range of applicability, and it is especially suitable for the filtration of small doses of material liquid.
- HD capsule filter
- The capsule filter of HD series has a variety of volumes for choices. Its cannulated connection for inlet and outlet has the advantages of quick installation and convenient use. The internal filter element can be configured with appropriate membrane material according to the characteristics of the filter material, which has a very wide range of applicability, and it is especially suitable for the filtration of small doses of material liquid.
- HB capsule filter
- The capsule filter of HB series has a variety of volumes for choices. Its cannulated connection for inlet and outlet has the advantages of quick installation and convenient use. The internal filter element can be configured with appropriate membrane material according to the characteristics of the filter material, which has a very wide range of applicability, and it is especially suitable for the filtration of small doses of material liquid.
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